改善子宫内膜容受性首先要针对原发病的治疗，如子宫内膜炎、子宫内膜异位症、多囊卵巢综合症、输卵管积水等。其次可采用以下方法：
内膜搔刮：晚黄体期/月经期时内膜结果疏松，便于清理，此时行内膜刺激术为佳，内膜搔刮有助于提高IVF-ET周期的种植率。其主要是损伤诱导子宫蜕膜化，增加白介素、组胺、上皮样生长因子等免疫分子，并使子宫内膜饱饮突出较前丰富，促进子宫内膜血管生成，改善容受性。
改善宫腔血流灌注：多囊卵巢综合症患者在卵泡期和黄体期子宫螺旋动脉的阻力指数升高，子宫血流减少，影响了胚胎着床。高雄激素血症、胰岛素抵抗、肥胖、血脂异常等都可能影响子宫血流灌注。因而可根据情况使用小剂量阿司匹林可抑制血小板活性，预防微血栓形成，改善局部血循环。
免疫球蛋白注射：母体封闭抗体产生障碍或不足可致流产，此时可给流产妇女注射免疫球蛋白，增加母体内封闭抗体，从而防止胚胎被母体免疫系统识别或误杀伤。
宫腔灌注：办子宫内膜厚度小于7mm时，使用130pg/ml浓度G-CSF进行宫腔灌注对子宫内膜厚度及容受性具有明显的改善作用。国内医院多使用中药进行宫腔灌注，但是否有效，仍需进一步试验和评价。
中药和针灸：补肾活血中药可改善子宫内膜容受性，有利于胚胎着床。针灸有可能通过调节子宫血流灌注促进内膜生长，改善子宫内环境，提高内膜容受性。
当然，每个病者有不同的差异，而且促排卵和自然周期子宫内膜也存在差异，因此，在任何IVF的治疗中，应根据病者的个体化情况调整种植窗口期开放时间，提供胚胎着床温馨的内环境，并做到观察调节激素与内膜发育同步、关注卵泡与内膜发育同步、关组内膜自身发育同步、个体化调节内膜间质与腺体发育同步。因而，在IVF-ET周期中，每个环节的评估与监控尤为重要。
文章来自: 播种网社区( www.bozhong.com) 详文参考：http://bbs.bozhong.com/thread-36751406-3-1.html

100 neu宫腔灌注

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I am about to start preparing for my next FET medicated cycle and I have another question for you: do you think that doing Neupogen washes before starting progesterone and HCG shots after progesterone start may be helpful? Could it instead bring any risk / make either one or both the drugs not work properly?
<br/> Thank you very

have now had 4 miscarriages with IVF single embryo transfers. 2 were chemical pregnancies and 2 made it to 8 weeks when the heart beat went away. The two that made it to 8 weeks were tested and determined normal male XY karyotype. The 4th miscarriage (chemical) was tested prior to transfer with CCS and was catagorized as a normal 5AA blast. I've always had chronic thin linings. Acupuncture has certainly helped, but hasn't completely fixed the problem. My E2 is always quite high (so I am absorbing it well) with little effect on my lining (we've tried estrace (oral and suppository), vivelle patches (least effective for me) and del estrogen IM shots (most effective) and of course daily baby aspirin over the years. Stims (creating natural estrogen) doesn't really seem to make a difference. This last cycle (chemical pregnancy), I was also following the Alan Beer clinic protocol and did 2 series of LIT to fix LADs (this worked and fixed my NK cells as well), humira (to correct for NK cells in lining and slight flux in TH1:TH2) and preventative IVIG before transfer. After this recent chemical pregnancy, my RE has suggested doing a Neupogen Uterine Wash. I was wondering how that fit in with other immunology treatments. I have heard that you should not do neupogen at the same time as IVIG but is this only when using neupogen subQ or is this for the wash as well? What about other immunology treatments such as humira? As with many others, I'm in a tough spot of trying to coordinate my western medical treatment (RE) with my alternative treatment (RI).
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<br/> Also, my RE has suggested trying a "scratch test" which is a therapeutic biopsy prior to starting the next FET meds. Any thoughts/successes on this approach?
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<br/> Thank you for your thoughts on this! I have heard tremendous things about the cutting edge ideas you bring to the table and the assistance you've given many couples to become and stay pregnant and truly appreciate any guidance you can provide me.
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I did a brief consult with Dr. Braverman in NYC and he suggested the Neupogen. He doesn't do the injections but actually does a uterine wash of the uterus prior to ET. If this fresh cycle doesn't work and we have some to freeze, we are going to consider the Neupogen for a FET.

Monday CD3-I go in for monitoring tomorrow morning. I am starting my 30mg of Lovenox (blood thinner) as well tomorrow morning and that injection is to be given in the morning now. Along with that I will take 500mg Metformin, 600iu Vitamin E, 25mg DHEA, 3 Maxi-Greens Capsules, and 50mg Viagra Suppository. At night I will take 5 units of Lupron, 300iu Follisitm, 300iu Menopur, 1000mg Metformin, 50mg Viagra Suppository, 3mg Melatonin, 25mg DHEA, 3 Maxi-Greens Capsules, 0.5mg Dexamethasone and a baby aspirin.
<br/>Friday CD7-Ultrasound and blood work to check response to stims.  
<br/>Saturday CD8-Uterine wash using 300mcg Neupogen
<br/>Monday CD10-Ultrasound and blood work, 2nd uterine wash with 300mcg Neupogen, and Heparin Anti-XA level to be drawn to see if my Lovenox dose is sufficient.  
<br/>Wednesday CD12-Ultrasound and blood work
<br/>Friday CD14-Ultrasound and blood work
<br/>After looking at the stim length of all of my previous IVFs, I am guessing that I will be triggering on Thursday or Friday (week after Thanksgiving) which would put my ER on Saturday the 3rd or Monday the 5th. Since we are shooting for a 5 day transfer my ET will either be on Thursday the 8th or Saturday 10th. It has already been decided that I will be transferring 4. Given my history, Dr. Braverman said that 4 should be our goal. For IVF #3 we transferred 8 Day 3 embryos (only after previous cycle CGH results indicated 2 normal out of 13) and that ended in a BFN, and so did our last cycle and we transferred 4 then.
<br/>300宫腔。

Neupogen-Yup, my insurance covered it!! After going back and forth with this, he has decided to hold off on the Sub Q injections and instead do uterine washes using it. The first uterine wash will be on CD7 or 8 and then the second 48 hours later. He said a 300mcg vial is diluted with 1cc saline and slowly injected like an IUI is done.
<br/>300加1cc盐水和人受一样滴。

"教授，真对不起,又辜负了您的精心治疗，我想这次又失败了。
<br/>....移植的第10天晚上12点左右，子宫的位置又象第9天晚上那样又疼了。今天是第12天，早上尿板几乎看不到第二条线。
<br/>....这回取卵的第2天，打了免疫球蛋白
<br/>....放了一个10 2 2 胚胎(孵化) 两个4BB的囊胚 (还有两个冻囊胚),放了之后打了肚皮针，美卓乐，阿斯匹林， 诺仕帕，穿心莲等等
<br/>....移植日 E2 1633 P>40
<br/>....移后第4天 E2 372.9 P 22.8 打1/3 艾泽
<br/>........第7天 打1/3 艾泽 挂抗宫缩的药水 晚上12点小腹一抽抽
<br/>....移后第8天 E2 2067 P>40 轻微腹水
<br/>........第9天 挂抗宫缩的药水 晚"